I've spent the morning shopping for music on itunes and came across this little gem from Across the Universe. "I Want To Hold Your Hand" performed by T.V. Carpio, who plays Prudence in the movie (I haven't seen it, but it's out on DVD).
The movie's characters and music are based on popular Beatles tunes and this version of "I Want To Hold Your Hand" is so haunting - I've been running down the batteries on my nano replaying this song.
And yes, the song is intended to be sung by a guy - "please let me be your man".... but in the movie, Prudence has a crush on her female friend.